How to install TOPCONS on local
TOPCONS is one of the many tools available used for transmembrane prediction in GPCRs. It uses prediction by several other prediction methods (scampi-msa, scampi-seq, prodiv, octopus, and pro) and based on which it, spits out the consensus topology. Length of each predicted transmembrane helix is 21. I have had a tough time installing TOPCONS. It had a huge number of dependencies. I thought sharing and contributing might help someone. Instructions: $ svn ls https://svn.sbc.su.se/repos/cbr/modhmm-projects/trunk/install_topcons.sh Run the above command to see install_topcons.sh on command prompt. If you do not see, then can be an issue with the SVN version you are using. To download the package mentioned at https://svn.sbc.su.se/repos/cbr/modhmm-projects/trunk/cmdline/ Use: svn co https: Prerequisites for installation: - SVN, bash, Linux environment - NCBI old blast . Old blast has binaries for blastall and formatdb. Add this into...